Injections, infusions & immunizations

96401 - RVUs & Medicare payment (2026)

Chemotherapy injection, subcutaneous or intramuscular.

Component	Non-facility	Facility
Work RVU	0.21	0.21
Practice expense RVU	1.90	1.90
Malpractice RVU	0.04	0.04
Total RVUs	2.15	2.15
National payment (CF $33.4009)	$71.81	$71.81
Qualifying APM payment (CF $33.5675)	$72.17	$72.17

How 96401 payment varies by locality

Medicare adjusts payment with geographic practice cost indices, so the same code pays differently across the 109 fee schedule localities. In 2026, non-facility payment for 96401 ranges from $62.22 in Arkansas (AR) to $100.01 in San Jose-Sunnyvale-Santa Clara (CA); calculate 96401 for your locality.

San Jose-Sunnyvale-Santa Clara (CA) $100.01 San Jose-Sunnyvale-Santa Clara (CA) $99.83 San Francisco-Oakland-Berkeley (CA) $97.77 San Francisco-Oakland-Berkeley (CA) $97.73 Napa (CA) $91.78 Vallejo (CA) $91.71 Seattle (WA) $86.32 Santa Rosa-Petaluma (CA) $85.87 National average $71.81 … 97 more localities between … Alabama (AL) $63.30 Rest Of Missouri (MO) $63.02 Mississippi (MS) $62.64 Arkansas (AR) $62.22

Non-facility payment for 96401 in the 2026 fee schedule ($33.4009 conversion factor), before sequestration. Gray bar = national average.

Global period: XXX

No global period: the global surgery concept does not apply to this code.

Related codes - injections, infusions & immunizations

96372 · therapeutic injection, subcutaneous or intramuscular
96365 · iv infusion for therapy, initial hour
96374 · iv push, single or initial drug
96413 · chemotherapy iv infusion, first hour
90471 · immunization administration, first vaccine
90472 · immunization administration, each additional vaccine
90460 · immunization administration with counseling, under 19, first component

Frequently asked questions

How much does Medicare pay for 96401 in 2026?

The national non-facility payment is $71.81 and the facility payment is $71.81, using the standard $33.4009 conversion factor. Actual amounts vary by Medicare locality; use the RVU calculator for your area.

What is the work RVU for 96401?

The 2026 work RVU for 96401 is 0.21. Total RVUs are 2.15 in the non-facility setting and 2.15 in the facility setting.

Why are the facility and non-facility amounts different?

Only the practice expense component changes by setting. In an office (non-facility) the practice bears the overhead, so the PE RVU is higher; in a hospital or ASC the facility bills its own overhead separately.

Source: CMS Physician Fee Schedule relative value file (rvu26c.zip, retrieved 2026-07-11). Service description is an original plain-English summary, not CPT descriptor text. CPT® is a registered trademark of the American Medical Association. Amounts are estimates before sequestration and claim-level adjustments.